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CASE STUDY · YRI FELLOW

From curious about COVID evolution to an IEEE conference acceptance

Sai conducted a genomic analysis of Omicron variant mutations, combining epidemiological analysis with evolutionary insight to understand how the virus evades immune responses. Using computational phylogenetics and genomic surveillance, she systematically cataloged spike protein mutations across lineages and identified 132 immune escape mutations. The findings inform vaccine development and pandemic preparedness.

FIELDBioinformatics & Genomics
RESULTAccepted at IEEE RCSM 2025
VENUEIEEE RCSM 2025, 2025
Sai Pasuparthi
Sai Pasuparthi, YRI FellowIEEE RCSM
BEFORE THE FELLOWSHIP

A high school student curious about how COVID variants evolve, with no prior experience in genomic analysis.

AFTER

IEEE conference accepted with a comprehensive analysis of Omicron mutations.

I analyzed 132 immune escape mutations in Omicron variants using genomic surveillance. YRI helped me get accepted to IEEE RCSM 2025.
SAI PASUPARTHI
THE LEDGER
01Accepted at the IEEE International Conference on Recent Computational Systems and Methods 2025
02Identified 132 immune escape mutations across Omicron lineages
03Applied computational phylogenetics and genomic surveillance methods
NEXT CASE STUDYNeil Voore, Elsevier journal submission

Every case study starts with one application.

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