Published a multi-cohort Bayesian model at IEEE CIBCB as a 10th grader
Working with YRI mentor Dr. Swetha MP, Srihaan designed a multi-cohort triangulation study integrating survey data, metagenomic sequencing and neuroimaging across three independent adolescent cohorts totaling 208 subjects. His Bayesian hierarchical structural equation model estimated direct, indirect and feedback effects across the stress-gut-metabolism axis. He found physiological stress associated with GI distress at beta 0.398, the gut microbiome acting as a metabolic hub at beta 0.767, and a stress-sleep correlation of 0.74.
A 10th grader interested in the gut-brain axis with clinical research exposure but no publication or computational research experience.
Published a multi-cohort Bayesian SEM framework at IEEE CIBCB in Greece, integrating behavioral, microbial and neuroimaging data.