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CASE STUDY · YRI FELLOW

From exploring research ideas to first-author IEEE publication in one summer

Nidhi arrived with two separate research interests and her mentor helped her combine them into one project. She built an AI-driven multi-omics framework integrating gut and skin microbiome data to identify non-invasive biomarkers for PCOS and autoimmune disorders, using FastQC, Trimmomatic, Bowtie2, Kraken2 and Bracken pipelines with Random Forest, XGBoost and LightGBM models. The paper was published at IEEE ICCCA 2025.

FIELDMedicine & Health
RESULTFirst-author IEEE publication
VENUEIEEE ICCCA 2025, 2025
Nidhi Kulkarni
Nidhi Kulkarni, YRI FellowIEEE
BEFORE THE FELLOWSHIP

An 11th grader with one literature review on COPD and some Python and AI experience, but no peer-reviewed publication.

AFTER

First-author IEEE publication combining AI and healthcare research with over 90% classification accuracy.

THE LEDGER
01First-author publication at the 2025 IEEE 7th International Conference on Computing, Communication and Automation
02Achieved over 90% classification accuracy
03Built a full multi-omics pipeline with FastQC, Trimmomatic, Bowtie2, Kraken2 and Bracken
04Applied SHAP and LIME analysis for model explainability
THE PAPERSkin Microbiome Signatures for Non-Invasive Detection of Autoimmune Disorders and Gut-Endocrine Axis Disruption in PCOS: An AI-Driven Multi-Omics ApproachVERIFY
NEXT CASE STUDYRuthwik Dhama, First-author IEEE publication

Every case study starts with one application.

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